Study on the Synergistic Prevention of Control Effect of Genetically Engineered Vaccines and Drug Sensitivity - Guided Medication for Porcine Bacterial Diseases

DOI: https://doi.org/10.62517/jlsa.202507311

Author(s)

Jun Li

Affiliation(s)

Foshan Surefire Agriculture and Animal Husbandry Co., Ltd., Foshan, Guangdong, China

Abstract

Aiming at the limitations of traditional prevention of control measures for bacterial diseases in pig farms, this study explored the synergistic prevention of control effect of genetically engineered vaccines and drug-sensitive guided medication for bacterial diseases in pig farms. During the research, by analyzing the core principles and application status of genetically engineered vaccines and drug-sensitive guided medication, and combining experimental data to analyze their synergistic prevention of control effect, this study provides a scientific guidance scheme for the prevention of control of bacterial diseases in pig farms.

Keywords

Bacterial Diseases in Pig Farms; Genetically Engineered Vaccines; Drug-Sensitive Guided Medication; Synergistic Prevention of Control; Antibiotic Resistance

References

[1]Petri F A M, Ferreira G C, Arruda L P, et al. Associations between pleurisy and the Main bacterial pathogens of the porcine respiratory diseases complex (PRDC)[J]. Animals, 2023, 13(9): 1493. [2]Fooladi S, Rabiee N, Iravani S. Genetically engineered bacteria: a new frontier in targeted drug delivery[J]. Journal of Materials Chemistry B, 2023, 11(42): 10072-10087. [3]Chen Y, Batra H, Dong J, et al. Genetic engineering of bacteriophages against infectious diseases[J]. Frontiers in microbiology, 2019, 10: 954. [4]Lin X, Jiao R, Cui H, et al. Physiochemically and genetically engineered bacteria: instructive design principles and diverse applications[J]. Advanced Science, 2024, 11(30): 2403156. [5]Agina O A. Application of advanced biotechnology tools in veterinary medicine[J]. Animal Research International, 2022, 19(3): 4604–4616-4604–4616. [6]Farrukh M, Munawar A, Nawaz Z, et al. Antibiotic resistance and preventive strategies in foodborne pathogenic bacteria: A comprehensive review[J]. Food Science and Biotechnology, 2025, 34(10): 2101-2129. [7]Salam M A, Al-Amin M Y, Salam M T, et al. Antimicrobial resistance: a growing serious threat for global public health[C]//Healthcare. MDPI, 2023, 11(13): 1946. [8]Bhattacharjee U, Sharma I. Integrating Modern Modalities for the Advancements and Enhanced Effectivity in Veterinary Medicine[M]//Biofilm Associated Livestock Diseases and their Management. Singapore: Springer Nature Singapore, 2025: 265-307. [9]Li F, Zhao H, Sui L, et al. Assessing immunogenicity of CRISPR-NCas9 engineered strain against porcine epidemic diarrhea virus[J]. Applied Microbiology and Biotechnology, 2024, 108(1): 248. [10]Mutuku C, Gazdag Z, Melegh S. Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches[J]. World Journal of Microbiology and Biotechnology, 2022, 38(9): 152.