Advances in Research on Sunscreen Peptides

DOI: https://doi.org/10.62517/jlsa.202607104

Author(s)

Zhu Youmin, Wang Xiaojing, Tian Yuncai

Affiliation(s)

Shanghai AZ Science and Technology Co., Ltd., Shanghai, China

Abstract

Prolonged or excessive exposure to ultraviolet (UV) radiation, particularly UVA and UVB, can cause significant skin damage, including sunburn, photoaging, immune suppression, and even skin cancer. Although conventional sunscreens are effective, they raise concerns regarding safety and environmental impact. As a result, the development of novel, safe, and eco-friendly sunscreen ingredients has become a key research focus. Sunscreen peptides-emerging UV protectants based on bioactive peptides-are gaining attention. This review systematically outlines the definition, classification, and mechanisms of action of sunscreen peptides, highlights current research progress and preclinical as well as clinical evidence for several major types, and thoroughly discusses the challenges facing their development. It also provides insights into future directions. Sunscreen peptides represent a highly promising strategy in photoprotection, potentially paving the way for the next generation of sunscreen products.

Keywords

Sunscreen Peptides; UV Protection; Cosmetics

References

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