Risk Factors Analysis of Post Anesthesia Induction Hypotension in Patients with Recurrent Nasopharyngeal Carcinoma

DOI: https://doi.org/10.62517/jmhs.202305201

Author(s)

He Luyao1,2

Affiliation(s)

1Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Guangzhou, China. 2Southern Medical University, Guangzhou, China.

Abstract

This study is to investigate the risk factors of post anesthesia induction(PIH) in patients with recurrent nasopharyngeal carcinoma. A retrospective analysis was conducted on the clinical data of 262 patients who underwent the nasal endoscopic surgery from January 2021 to May 2023 were into this study. These patients were divided into group A(patients of non-PIH) and group B(patients of PIH). Univariate analysis and multivariate Logistic regression analysis were performed to analyze the independent risk factors of PIH. The overall incidence rate of PIH was 17.56%. According to the univariate analyses, anesthetics used for induction (dexmetomidine) and Preoperative serum sodium level were significantly correlated with PIH in patients with recurrent nasopharyngeal carcinoma(p<0.05). Furthermore, multivariate logistic regression prediction model identified the two indicators above are independent risk factors for PIH in patients. The model fit well, and the area under the receiver operating characteristic curve was 0.676, and the predictive sensitivity and specificity were 78% and 53.2%, respectively. The results of this paper show that, anesthetics used for induction (dexmetomidine) and Preoperative serum sodium level were independent risk factors for PIH. It provides theoretical foundation for predicting PIH after splenectomy.

Keywords

Recurrent Nasopharyngeal Carcinoma; Nasal Endoscopic Surgery; Post-induction Hypotension

References

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