Application of Percutaneous Vertebroplasty Assisted by 3D Printed Positioning Guide Plate in the Treatment of Senile Osteoporotic Vertebral Compression Fractures

DOI: https://doi.org/10.62517/jmhs.202305303

Author(s)

Wei Zhang, Zhehui Zhu, Shizhang Liu, Huitong Liu*

Affiliation(s)

Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China *Corresponding Author.

Abstract

This paper aims to investigate the feasibility, treatment points, and clinical effects of percutaneous vertebroplasty (PVP) assisted by 3D printed individual positioning guides for senile osteoporotic vertebral compression fractures (OVCF). Percutaneous vertebroplasty assisted by 3D printed individual positioning guides were used to treat 30 diseased vertebrae of 30 elderly female patients with compression fractures. The NRS and ODI score were compared before the operation, 1 day after the operation, 1 week after the operation, 1 month and 3 months after the operation. All patients successfully completed the operation, and followed up for 3 months. Through statistical analysis of patients’ NRS scores and ODI scores, the difference was significantly improved 1 day before and after surgery (P <0.001), and there was no statistical difference between 1 and 3 months after surgery (P>0.05). The improved Macnab score was excellent and good rate Reaching 97%. Preoperative 3D printed individual positioning guide assisted positioning help to reduce the radiation exposures, surgical risks, shorten the surgical time, and obtain good curative effects, high safety, and clinical application value.

Keywords

3D Printing; Personalized Positioning Guide Plate; Percutaneous Vertebroplasty (PVP); Osteoporotic Vertebral Compression Fracture (OVCF)

References

[1]Zeng Q, Li N, Wang Q, et al. The Prevalence of Osteoporosis in China, a Nationwide, Multicenter DXA Survey. J Bone Miner Res. 2019, 34 (10):1789-1797. [2]Bessette L, Ste-Marie LG, Jean S, et al. The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int. 2008, 19 (1):79-86. [3]Osteoporosis prevention and rehabilitation committee, Chinese association of rehabilitation medicine. Consensus on the diagnosis and treatment of osteoporotic vertebral compression fractures (2021). Zhonghua Yi Xue Za Zhi, 2021, 101 (41): 3371-3379. [4]Kutsal FY, Ergin Ergani GO. Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turk J Med Sci. 2021, 51 (2): 393-399. [5]Yu Y, Li C, Yao H, et al．PVP in the treatment of elderly osteoporotic vertebral compression fracture: clinical analysis of 71 cases. Journal of Clinical and Experimental Medicine, 2012, 11 (18): 1476-1477. [6]Fu H, Liu J, Wu R, et al. Treatment of senile osteoporotic compression fractures with vertebroplasty. Inner mongolia medical journal, 2016, 48 (11): 1319-1320. [7]Galibert P, Deramond H, Rosat P, et al. Preliminary note on the.treatment of vertebral angioma by percutaneous acrylic vertebroplasty .Neurochirurgie, 1987, 33: 166-168. [8]Osteoporosis Group of Chinese Orthopaedic Association. Guideline for diagnosis and treatment of osteoporotic fractures. Chinese Journal of Orthopaedics, 2017, 37 (1): 1-10. [9]Hu P, Lin J, Fei Q, et al. A novel percutaneous vertebroplasty assisted by three-dimensional printed guide template for double-segment osteoporotic vertebral compression fracture: technical report. The journal of cervicodynia and lumbodynia, 2021, 42 (5): 597-601. [10]Balkarli H,Demirtas H,Kilic M,etal. Treatment of osteoporotic vertebral compression fractures with pereutaneous vertebroplasty underlocal anesthesia:clinical and radiologieal results. Int J Clin Exp Med, 2015, 8 (9) :16287-16293. [11]Zhang G, Ge B. Percutaneous vertebroplasty complications. China Journal of Orthopaedics and Traumatology, 2013, 26 (3) :257-260. [12]Al - Nakshabandi, NizarA. Percutaneous vertebroplasty complications. Ann Saudi Med, 2011, 31 (3) :294-297. [13]Saracen A, Kotwica Z. Complications of percutaneous vertebroplasty: An analysis of 1100 procedures performed in 616 patients. Medicine, 2016, 95 (24): e3850. [14]Lin BJ, Li CC, Ma HI. Intradural cement leakage after percutaneous vertebroplasty. Turkish Neurosurgery, 2014, 25 (6): 940 [15]Hu P, Lin J, Xu J, et al. Three-Dimensional printing guide template assisted percutaneous vertebroplasty (PVP). JVis Exp, 2019, 152: e60010. [16]Fitousi NT, Efstathopoulos EP, Delis HB, et al. Patient and Staff Dosimetry in Vertebroplasty. Spine, 2006, 31 (23): E884 -E889. [17]Zhang Y, Zhang L, Sun R et al. A new 3D printed titanium metal trabecular bone reconstruction system for early osteo - necrosis of the femoral head. Medicine, 2018, 97 (26): e11088. [18]Park HJ,Wang C,Choi KH,et a1. Use of a life size three dimensional-printed spine model for pedicle screw instrumentation training. J Orthop Surg Res, 2018, 13 (1): 86. [19]Zheng P, Yao Q, Xu P et al. Application of computer-aided design and 3D-printed navigation template in Locking Compression Pediatric Hip Plate TM placement for pediatric hip disease. Int J Comput Assist Radiol Surg, 2017, 12 (5): 865-871. [20]Hu P, Lin J, Fei Q. Clinical applications of 3D printing individualized guide template in the spinal surgery. International Journal of Surgery, 2018, 46 (7): 481-485. [21]Kaneyama S,Sugawara T, Sumi M. Safe and accurate midcervical pedicle screw inseaion procedure with the patient·specific screw guide template system. Spine, 2015, 40 (6): E341-348 [22]Ni P, Liu D, Zhang Y, et al. Application of 3D printing individualized guide plate in percutaneous vertebroplasty. Chinese Journal of Bone and Joint Injury, 2017, 32 (11): 1131-1134. [23]Wang X, Pan Z, Guo D. Analysis of early efficacy and influencing factors of percutaneous kyphoplasty for the treatment of elderly patients with osteoporotic thoracolumbar vertebral fractures. The journal of cervicodynia and lumbodynia, 2021, 42 (5): 713-715.