The Correlation between Changes in Serum Sodium and Hospital Mortality in Critically Ill Children with Acute Kidney Injury

DOI: https://doi.org/10.62517/jmhs.202405101

Author(s)

Yue Yan1#, Yu Han2#, Xuan Zhang1,*, Xiangkui Li3, Hao Zhu1,*, Jing Liu1, Yinxu Liu1, Jing Zhang1, Hao Wang1, Luyao Zhou1

Affiliation(s)

1 College of Physics and Information Engineering, Zhaotong University, Zhaotong, Yunnan, China 2 Rolling car room, Hongta Tobacco (Group) Co., Ltd. Dali Cigarette Factory, Dali, Yunnan, China 3 College of Computer Science and Technology, Harbin University of Science and Technology, Harbin, Heilongjiang, China # These authors contributed equally to the research. * Corresponding Author

Abstract

For critically ill patients with acute kidney injury (AKI), early warning and intervention can be achieved through monitoring serum sodium levels. However, the normal range of serum sodium levels in AKI patients in the intensive care unit (ICU) is not yet clear. This article aims to use statistical methods to study the relationship between changes in serum sodium and hospital mortality in critically ill children with acute kidney injury. This article conducted a retrospective observational cohort study on multiple critically ill children with acute kidney injury using the China Large Pediatric Intensive Care Database to demonstrate that serum sodium levels as an independent predictor can be used to evaluate the hospital mortality rate of critically ill children with AKI. A total of 1505 eligible critically ill children with acute kidney injury were included in the study. The research results indicate that the normal range of serum sodium in children with AKI is approximately 135 to 142mmol/L. The increase or decrease in serum sodium concentration in critically ill children with acute kidney injury admitted to ICU is associated with in-hospital mortality. Therefore, in the ICU, it is necessary to continuously monitor and evaluate the serum sodium levels of children with acute kidney injury to prevent death due to the progression of the disease.

Keywords

Serum Sodium; Intensive Care Unit; Acute Kidney Injury; Mortality Rate; Children

References

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