Clinical Observation of Silk Fibroin Composite Gel Combined with CO2 Lattice Laser in the Treatment of Facial Acne Depressed Scar

DOI: https://doi.org/10.62517/jmpe.202618208

Author(s)

Wu Tao, Wu Jiang, Zheng Lingli, Xu Cai*

Affiliation(s)

First People's Hospital of Longjiang, Longjiang, China *Corresponding Author

Abstract

This study aims to observe the clinical effect and safety of silk fibroin composite gel combined with CO2 fractional laser in the treatment of facial atrophic acne scars. A total of 98 patients with facial atrophic acne scars were selected and randomly divided into a study group (n=49) and a control group (n=49). Both groups received CO2 fractional laser treatment. After the laser surgery, the control group used standard hyaluronic acid (HA) dressing, and the study group used silk fibroin composite gel (Siruimei Biotechnology). The clinical effect, ECCA scar score, patient satisfaction, and adverse reactions were compared between the two groups. The results showed that the total effective rate of the study group was 97.96% (48/49), which was significantly higher than 83.67% (41/49) of the control group (P<0.05). After treatment, the ECCA score of the study group (48.42 ± 6.35) was significantly lower than that of the control group (56.82 ± 7.12) (P<0.05). The total patient satisfaction rate in the study group (93.88%) was significantly higher than that in the control group (75.51%) (P<0.05). The incidence of adverse reactions in the study group was 8.16% (4/49), which was significantly lower than 24.48% (12/49) in the control group (x2 = 4.89, P<0.05). In conclusion, silk fibroin composite gel combined with CO2 fractional laser has a very good clinical effect on facial atrophic acne scars. It can improve the scar appearance, improve patient satisfaction, and reduce complications safely.

Keywords

Silk Fibroin Composite Gel; CO2 Fractional Laser; Atrophic Acne Scars; Wound Healing; ECCA Score

References

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